乳腺癌已成为中国女性最常罹患的恶性肿瘤,肿瘤绿色治疗已成为趋势,所以,研发"增效减毒"的抑制乳腺癌细胞增殖的药物对乳腺癌治疗具有十分重要的意义.姜黄素作为中草药姜黄根茎的活性提取物,因其有效抑制乳腺肿瘤细胞增殖,改善患者预后,有效减轻乳腺癌化疗后反应,正被越来越多的研究人员和临床医生青睐,成为研究的焦点.该文就姜黄素抑制乳腺癌增殖的分子机制,姜黄素剂型和载药系统,姜黄素联合放疗和化疗增效减毒的体内外实验研究进展进行综述.%Breast cancer has become one of the most frequently-occurred malignant tumors among Chinese women, while green therapy has turn into a new trend of tumor treatment. Therefore, exploration of new anti-cancer drugs has important significance for treatment of breast cancer. Curcumin, as an active ingredient of turmeric, was paid more attention by researchers and doctors, due to its inhibition of tumor cell proliferation, improving prognosis, reducing the reaction after chemotherapy. This article summarized the new research development of breast cancer cell's proliferative inhibition mechanisms of drug delivery system of curcumin, function of synergy and attenuation of curcumin allying with chemotherapy and radiotherapy.
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