两种方法检测特应性皮炎患儿对海产品过敏的比较

摘要

目的:评价皮肤点刺试验和抗原特异性IgE抗体检测法对特应性皮炎患儿海产品过敏检测的一致性.方法:应用皮肤点刺试验及酶联免疫方法对105例特应性皮炎患儿进行鱼、虾、蟹类食物过敏原测定,并比较两者的差异.结果:皮肤点刺试验结果显示对鱼类、虾类及蟹类过敏原阳性者分别为37例(35.2％)、32例(30.5％)及23例(21.9％),抗原特异性IgE抗体测定阳性者分别为23例(21.9％)、11例(10.5％)及20例(19.0％)；两者的一致性分别为0.18、0.12及0.16.结论:两种检验结果的一致性较差,不可相互代替使用于特应性皮炎的检测.%Objective: To assess the agreement of skin prick test (SPT) and allergen- specific IgE (slgE) in therndetection of marine food allergens in patients with atopic dermatitis (AD). Methods: SPT and allergen - specificrnIgE using ELBA were performed to test marine food allergens in 105 children with AD. The agreement of the tworntests was assessed. Results: With skin prick test,37 patients (35.2%) were positive to fish allergen, 32 (30.5%)rnto shrimp and 23 (21.9% ) to crab, respectively. With slgE, the number of positive patients was 23 (21.9%) tornfish, 11 (10.5%) to shrimp and 20 (19.0%) to crab. The Kappa values of the two tests were 0.18, 0.12 andrn0.16, respectively. Conclusion: The agreement of the two tests was poor, and they are not substituted in place ofrnanother in the testing of AD.