[Objective] To evaluate the outcome of the laparoscopic appendectomy and define the learning curve for the laparoscopic appendectomy. [Methods] Consecutive patients with acute appendicitis who underwent (LA) from 2009 to 2010 were reviewed. The patients were divided into six groups (11 cases in each group) by operative sequence. Data on patient demographics, clinical and outcome variables including operative duration, conversion to open surgery, complications, and length of stay were analyzed. The learning curve for the laparoscopic appendectomy was established through the moving average and ANOVA methods. [ Results ] There was no significant difference a— mong the patients in the six different phases with respect to age, sex, weight and pathology. The patients were divided into group A who underwent the operation in the early period (before the learning curve) and group B who underwent the operation in the later period (after the learning curve). The average operative duration for group A was (76± 17.5) minutes, but it was (56±14.8) minutes for group D (P =0.000). There was three patients converted to open surgery in group A. group B was one case, there was a slightly higher in group A, but it was no statistical significance. Significant differences were not shown in the hospitalization period and infectivity complications. [Conclusion ] Operative duration and conversion can be reduced with increasing experience of LA, In this study, the learning curve for a laparoscopic appendectomy was about thirty cases.%目的 评估腹腔镜阑尾切除术不同时期手术时间及并发症,探讨腹腔镜阑尾切除术的学习曲线.方法 回顾性分析2009年7月～2010年12月66例行腹腔镜阑尾切除术患者的临床资料,按手术先后次序分6组,每组11例,比较各组手术时间、中转率、住院时间及术后感染性并发症.通过移动平均组线及方差分析来界定腹腔镜阑尾切除术学习曲线.结果 各组病例年龄、性别、体重及病理等方面差异无显著性(P＞0.05),学习曲线早期(A组)平均手术时间为(76.0±17.5)min,学习曲线后期(B组)手术时间为(56.0±14.8)min,两组比较差异有显著性(P=0.000)；A、B两组分别有3例及2例中转进腹,A组较B组有轻微升高,但差异无显著性(P=0.642)；两组术后住院时间及感染性并发症进行比较,差异无显著性.结论 手术时间及中转率可随着临床病例的增加而逐步降低,腹腔镜阑尾切除术的学习曲线约为30例.
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