2型糖尿病伴高尿酸血症与血清25(OH)D水平相关性研究

摘要

目的 探讨2型糖尿病合并高尿酸血症与血清25(OH)D水平的相关性.方法 420例2型糖尿病患者分为单纯2型糖尿病组(A组)和2型糖尿病伴高尿酸血症组(B组),比较两组临床指标差异以及高尿酸血症与血清25(OH)D的相关性.结果 B组BMI、TC、TG、LDL-C高于A组(P<0.01).血尿酸水平与血清25(OH)D水平呈负相关(r=-0.121,P<0.05).结论 2型糖尿病伴高尿酸血症血清25(OH)D低下,低水平血清25(OH)D可能是2型糖尿病伴高尿酸血症的危险因素.%Objective To discuss the relationship between 2 type diabetes melitus and serum 25(OH)D.Methods 420 cases of type 2 diabetic patients were divided into type 2 diabetic group(A group)and type 2 diabetes melitus with hyperuricemia group(B group). To compare the difference of clinical indexes of two groups,and correlation between hyperuricemia and serum 25(OH)D.Results BMI、TC、TG、LDL-C of B group were obviously higher A group(P<0.01). Serum uric acid level was negatively correlated with serum levels of 25(OH)D(r=-0.121,P<0.05). Conclusion Type 2 diabetes melitus with hyperuricemia in patients has low serum 25(OH)D. Low levels of serum 25(OH)D may be the risk factors for type 2 diabetes melitus with hyperuricemia.