鞍山市2013年疑似预防接种异常反应监测数据分析

摘要

目的分析2013年鞍山市疑似预防接种异常反应（Adverse Events Fol owing Immunization，AEFI）的发生特征，为改善AEFI监测工作提供依据。方法收集中国疑似预防接种异常反应信息管理系统中报告的鞍山市AEFI个案数据，采用描述性流行病学方法进行分析。结果2013年鞍山市共报告AEFI189例，报告发生率为32.27/10万剂次。其中一般反应177例（93.65%），异常反应7例（3.7%），偶合症5例（2.65%）。男女性别比为1.49：1，0～1岁儿童占80.42%。报告例数排前位的疫苗分别是百白破疫苗、麻风疫苗、白破疫苗，报告发生率居前位的疫苗分别是麻风疫苗、白破疫苗、百白破疫苗。87.83%的AEFI发生在接种疫苗后0～1d。96.82%的AEFI治愈或好转，5.82%AEFI住院，无死亡个案。结论 AEFI主要发生于接种国家免疫规划疫苗后，多在小年龄儿童接种首剂疫苗后的2d内发生，以一般反应为主。鞍山市AEFI监测系统有较高敏感性。%Objective To analyze the occurrence characteristics of Adverse Events Fol owing Immunization(AEFI) in Anshan 2013. Methods To col ect Anshan AEFI case data reported in Chinese suspected AEFI information management system, and analyze with descriptive epidemiological methods. Results 189 AEFI cases were reported in Anshan in 2013( the report incidence rate was 32.27/10 mil ion doses. Among them 177 were general reaction (93.65%), 7(3.7%) were abnormal reaction,5 (2.65%) were coincidence. The ratio between male and female was 1.49:1, 80.42%were 0~1 year old babies. Top reported vaccine were DPT,MMR vaccination,white broken vaccine.87.83%AEFI occurred 0-1 dayafter taking vaccination. 96.82%AEFI were cured or improved,and 5.82%were in hospital,no death case was reported. Conclusion AEFI mainly occurred after taking national immunization vaccine,most occurred within 2 days after young children taking first dose of vaccine with general reaction. The AEFI monitoring system in Anshan was much more sensitive.