Objective To investigate the curative ef ects and gastric dynamic index change of Domperidone on dif erent TCM syndrome types in patients with functional dyspepia( FD) . Methods 60 cases of FD with gastric dyskinesia patients were divided into 2 groups:spleen-deficiency-qi-stagnation group(30 cases)and liver-qi-stagnation group(30 cases).Another 10 healthy volunteers were selected as nomal control.The FD patients were treated with Domperidone Tablets 5mg,3 times a day,oral 30 minute before meal,for 15 days.To observe the total ef ective rate of symptoms and single symptoms,and the changes of elecrogastrogram,compared with those of the normal group.Result After treatment,the total score of FD group and the ef ec-tive rate of single symptom were al improved(P<0.05).The clinical ef ective rate of spleen -deficiency-qi-stagnation group was obviously bet er than that of liver -qi-stagnation(86. 7%v50%)(P<0.05).Compared with the normal group the liver-qi-stagnation group and spleen-deficiency-qi-stagnation group had obvious abnormity in gastric electrogram rhythm before treatment(P<0.05).While their gastric electrogram rhythm had been improved after treatment.Preprandial and postprandial normal slow waves of elecrogastrogram and electric power were improved(P<0.05),but the spleen-deficiency-qi-stagnation group was bet er than the liver-qi-stagnation group in total ef ective rate and partly gastric dynamics index(P <0. 05).Conclusion The clinic ef ectiveness of Domperidone Tablets for FD patients with TCM diagnosis of spleen -deficiency -qi -stagnation and gastric dyskinesia is significant.Functional dyspepsia.%目的：研究多潘立酮对不同证型功能性消化不良患者胃动力的影响及临床疗效研究。方法确诊的 FD 运动障碍型患者60例：肝郁气滞型30例，脾虚气滞型30例，另选10例健康查体者做正常对照组．两证型患者均给予多潘立酮片10mg日3次，饭前30分钟口服，疗程15天。观察治疗前后两证型患者的临床疗效及胃电图变化。结果治疗后脾虚气滞组的症状积分小于肝郁气滞组，且脾虚气滞组的总效率86．7％，高于肝郁气滞组50％，差异显著（x2＝2．58p ＜0．05）治疗后两组的胃电节律较治疗前明显改善。治疗前两组餐前后的胃电功率均低于正常组，但肝郁气滞组与正常组相比，无差异性p＞0．05）。治疗后餐前餐后的胃电功率增加，脾虚气滞组的餐前餐后胃电功率增加，差异显著p＜0．05）。肝郁气滞组餐前后的增加无差异性。结论多潘立酮对不同证型的消化不良患者临床疗效不同，对脾虚气滞组的临床疗效好于肝郁气滞组。
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