分析大剂量沐舒坦在胸部创伤所致肺挫伤中的应用效果。方法收集2012年06月—2014年6月该院收治的66例胸部创伤所致肺挫伤患者临床资料，按照不同的剂量方法，将患者分为大剂量组33例、小剂量组33例。两组患者均采取常规综合治疗，大剂量组患者加以大剂量沐舒坦治疗，小剂量组患者加以小剂量沐舒坦治疗，最后分析两组患者的临床治疗效果。结果与小剂量组治疗有效率57.58%对比，大剂量组患者治疗总有效率明显更高为84.85%(P<0.05)。与小剂量组患者肺部感染、肺不张并发症发生率30.30%对比，大剂量组患者并发症发生率明显更低为9.09%(P<0.05)。治疗后，在PaO2、PaCO2、SaO2等指标改善方面，大剂量组患者明显优于对照组(P<0.05)。结论大剂量沐舒坦治疗胸部创伤所致肺挫伤，疗效显著，有利于降低肺部并发症发生率，促进肺功能恢复，值得临床推广。%Objective To analyze the application effect of large dose of mucosolvin on pulmonary contusion caused by chest trau-ma. Methods The clinical data of 66 cases with pulmonary contusion caused by chest trauma admitted in our hospital from June 2012 to June 2014 were selected. The patients were divided into the large dose group and small dose group with 33 cases in each according to the different dose used. Based on the conventional comprehensive treatment, the large dose group was given large dose of mucosolvin and small dose group was given small dose of mucosolvin for treatment. And the clinical treatment effects of the two groups were analyzed. Results The total effective rate of the large dose group was 84.85%, significantly higher than 57.58%of the small dose group(P<0.05). The incidence of complications such as lung infection and atelectasis of the large dose group was 9.09%, much lower than 30.30% of the control group (P<0.05). After treatment, the improvement in PaO2, PaCO2, SaO2 and so on of the large dose group was obviously better than that of the control group (P<0.05). Conclusion For pulmonary contusion caused by chest trauma, large dose of mucosolvin has distinct curative effect, which is conducive to reducing the incidence of pul-monary complications, and promoting the recovery of the lung function, so it is worth clinical promotion.
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