Objective To observe the effect of salbutamol combined with ambroxol inhalation in treatment of acute exacerbation of chronic obstructive pulmonary disease. Methods Choose in respiratory department of our hospital, During May 2013 to May 2015 in chronic obstructive lung disease acute episodes of hospitalization patients, 190 cases, were randomly assigned to control group and observation group, each group of 95 cases. Patients in the control group were treated by low flow oxygen, eliminating phlegm and relieving asthma, control infection and other routine treatment; observation group in the conventional treatment on the basis of using salbutamol and Ambroxol Aerosol Inhalation. Two groups of treatment for 10 days. The pulmonary function index of the two groups were observed, and the clinical effect of the two groups were compared. Results In the treatment of two groups of patients lung function index FEV1, FVC and FEV1/FVC (P<0.05). The two groups of patients with FEV1 and FEV1/FVC levels before and after treatment had different degrees of improvement and the observation group to enhance the degree of the superior to the control group and observation group, FEV1, FVC and FEV1/FVC were higher than the control group (P<0.05). Clinical curative effect of total efficiency (92.6%) was significantly better than the control group (75.8%). Conclusion Salbutamol and Ambroxol Aerosol Inhalation can effectively improve the pulmonary function in treatment of patients with acute exacerbation of chronic ob-structive pulmonary disease, quickly alleviate the symptoms of respiratory system.%目的 分析沙丁胺醇联合氨溴索雾化吸入治疗慢性阻塞性肺疾病急性发作的效果. 方法 整群选择该院呼吸内科2013年5 月-2015 年 5月的慢性阻塞性肺疾病急性发作住院患者190例,随机分为对照组和观察组各95例,对照组给予化痰解痉平喘、低流量吸氧和控制感染等常规基础治疗;在常规治疗基础上对观察组采用沙丁胺醇联合氨溴索雾化吸入治疗,两组的疗程都为 10 d. 分别观察治疗前后两组患者的各项肺功能指标,并对两组的临床疗效进行比较分析. 结果 治疗前两组患者的肺功能指标FEV1 、FVC 水平和 FEV1/FVC,P>0.05;治疗后两组患者 FEV1和 FEV1/FVC 水平均较治疗前有不同程度的提升,且观察组提升程度优于对照组,观察组FEV1 、FVC 水平和 FEV1/FVC 均高于对照组,P<0.05;临床疗效总有效率(92.6%)明显优于对照组(75.8%). 结论 沙丁胺醇联合氨溴索雾化吸入疗法可迅速缓解患者呼吸系统症状,有效改善慢性阻塞性肺疾病急性发作患者的肺功能.
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