Objective For severe craniocerebral injury patients with acute upper gastrointestinal hemorrhage and the clinical symptoms of intractable hiccup were analyzed deeply, the study of the pathogenesis and clinical commonly used method of treatment. Methods 24 cases of severe craniocerebral and intractable hiccup for information about injury of acute upper gastrointestinal hemorrhage were chosen in August 2012~August 2014.Results After treatment, 24 patients were cured (83.3%), 4 cases died (16.7%).Conclusion After a lot of severe craniocerebral injury patients of acute upper gastrointestinal bleeding and combined to produce condition of intractable hiccup were more serious and has a high mortality rate. In the clinical treatment should be paid much more attention.%目的：针对重型颅脑损伤急性上消化道出血并顽固性呃逆患者的临床症状进行较深入地分析，研究探讨其发病机制及临床常用治疗方法。方法收集2012年8月～2014年8月临床中的24例重型颅脑损伤急性上消化道出血并顽固性呃逆患者的有关资料。结果24例患者经临床治疗后，有20例患者治愈（占83.3%），4例死亡（占16.7%）。结论很多重型颅脑损伤后患者都会出现急性上消化道出血，而合并产生顽固性呃逆患者的病情更加严重，具有较高的死亡率，在临床治疗中应特别引起重视。
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