Objective To evaluate the clinical effect of Pegasys combined with Leigh Bhave Lin in the treatment of chronic hepatitis C. Methods 82 cases selected from our hospital in patients with chronic hepatitis C, were randomly divided into control group and observation group, the control group using conventional interferon Gary Bhave Lin treatment, the observation group with Pegasys treatment on Gary Bhave Lin. To compare the effects of two groups. Results The observation group early response rate and complete response rate was significantly higher than the control group, no efifciency is signiifcantly lower than the control group, P<0.05. There was no significant difference in the incidence of adverse reactions Conclusion Pegasys combined therapy for chronic hepatitis C Leigh Bhave Lin signiifcant curative effect, can improve the early response rate, and high safety , is worth in clinical application.%目的：分析聚乙二醇干扰素α-2a注射液（派罗欣）联合利巴韦林治疗慢性丙肝的临床疗效。方法选取于本院就诊的慢性丙肝患者82例，随机分成对照组和观察组，对照组采用常规干扰素加利巴韦林治疗，观察组采用派罗欣加利巴韦林治疗。比较两组患者的疗效。结果观察组患者的早期应答率和完全应答率明显高于对照组，无效率明显低于对照组，P＜0.05，两组患者不良反应发生率对比差异无统计学意义（P＞0.05）。结论派罗欣联合利巴韦林治疗慢性丙肝疗效显著，能有效提高早期应答率等，安全性高。
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