颈动脉内膜中膜厚度与冠心病发病及冠状动脉病变严重程度的相关性分析

摘要

目的：探讨颈动脉内膜中膜厚度（IMT）与冠心病（CHD）发病及冠状动脉病变严重程度的关系。方法收集1415例疑诊CHD患者进行回顾性分析，均测定颈动脉IMT，以冠脉造影阳性作为诊断CHD的标准，将全部患者分为CHD组及非CHD组，分析颈动脉IMT与冠心病发病及冠状动脉病变严重程度。结果 CHD组颈动脉IMT增厚的比例显著高，且随冠脉病变程度加重，颈动脉IMT亦增厚。Gensini积分和冠脉病变支数，与颈动脉IMT呈线性正相关（P＜0.001），颈动脉IMT与冠心病存在显著关联。结论颈动脉IMT增厚与冠状动脉病变严重程度密切相关，为冠脉病变的独立危险因素。%Objective To examine the relationship between carotid artery intima-media thickness (CCA-IMT) and extent of coronary heart disease (CHD). Methods After diagnosed by coronary angiography (CAG), 1 415 patients were divided into CHD group and non-CHD group. In all patients, CCA-IMT was measured by color Doppler ultrasound. Then, the relationship between CCA-IMT and CHD was analysed. Results The result is that the more serious of CHD, the thicker in CCA-IMT. CCA-IMT correlated positively with Gensini score of coronary artery and number of stenotic coronary arteries. Conclusion Between CCA-IMT and the level of CHD exist obviously dependability. CCA-IMT has independent positive correlation with CHD, are independent protective factors of CHD.