浅析宫颈病变患者人类乳头瘤病毒基因分型

摘要

目的：分析宫颈病变患者人乳头瘤病毒HPV基因分型情况。方法对收治的150例宫颈病变的患者，先门诊行宫颈脱落细胞检查或宫颈刮片检查，对可疑病变患者再行阴道镜检查及镜下定位活组织检查，然后应用HPV-DNA进行检测，分析患者的HPV分型情况。结果150例患者中检出HPV阳性120例，阳性率为80.0%；其中高危型51例，低危型27例，中国人常见型7例；复合型35例；而高危型的HPV 16、58，低危型HPV 11以及复合型的感染率比较高；50岁以上的患者感染HPV的几率最高。结论宫颈病变患者中HPV感染亚型的16、58和11比较高，因此在预防和治疗中要引起相关的注意。%Objective To analyze the HPV genotyping of human papillomavirus in patients with cervical lesions.Methods 150 cases of cervical lesions in patients with first outpatient cervical shedding cells check or cervical scraping smear, in patients with suspicious lesions and vaginoscopy and mirror positioning biopsy then applied HPV-DNA detection, analysis in patients with HPV types.Results 150 patients, detected in 120 cases of HPV positive, the positive rate was 80.0%; among high risk type in 51 cases, low-risk type in 27 cases, 7 cases of common type in Chinese people; composite type 35 cases; and high-risk types of HPV 16, 58, low-risk HPV type 11 and composite type of infection rate is relatively high; patients over the age of 50 sense staining of HPV are most likely.Conclusion 16, 58 and 11 of HPV infection in patients with cervical lesions are relatively high, so the attention should be paid to the prevention and treatment of cervical lesions.