肝硬化门静脉高压症术后门静脉血栓形成危险因素研究

摘要

Objective To explore the risk factors of portal vein thrombosis after surgery for cirrhotic portal hypertension. Methods 102 patients with cirrhotic portal hypertension surgery were selected. Based on whether had portal vein thrombosis, the patients were divided into observation group (with portal vein thrombosis) and control group (without portal vein thrombosis). The changes of haemodynamics, PT, D-D, Fib, PLT and cholesterol were observed and compared. Results Compared with control group, there were wider portal vein diameter, slower portal blood flow, increased portal vein pressure, higher levels of D-dimer and cholesterol in observation group. The differences between the two groups were statistically significant (P<0.05). Conclusion It is necessary to detect the level of haemodynamics, D-dimer and cholesterol before and after operation for the prevention of portal vein thrombosis after surgery for cirrhotic portal hypertension.%目的探讨肝硬化门静脉高压症术后门静脉血栓形成的危险因素。方法102例肝硬化门静脉高压症手术患者，根据术后有无门静脉血栓形成分为观察组（门静脉血栓形成）和对照组（无门静脉血栓形成），比较两组门静脉血流动力学及PT、D-D、Fib、PLT、血胆固醇变化情况。结果与对照组比较，观察组门静脉直径增宽，血流速度降低，压力升高，血胆固醇、D-二聚体水平比例高，差异有统计学意义（P＜0.05）。结论术前、术后密切监测门静脉血流动力学及血D-二聚体、胆固醇水平对预测肝硬化门静脉高压症术后门静脉血栓形成具有重要意义。