不拉氏酵母菌在预防小儿抗生素相关性腹泻中的疗效评价

摘要

Objective To study and explore the clinical efficacy of Saccharomyces boulardii in the prevention of pediatric antibiotic associated diarrhea.Methods From January 2014 to December 2015, 240 patients treated with antibiotics were selected as the research object, and were randomly divided into the control group and observation group using the method of throwing coins, 120 cases in each group. Two groups of patients were given antibiotics and symptomatic treatment, observation group was added with Saccharomyces boulardii.Results The secondary diarrhea incidence rate of the observation group was 9.17%, which was signiifcantly lower than the control group of 20.83% (P<0.05). Compared with the control group, the duration time of diarrhea patients in the observation group was significantly shorter (P<0.05).Conclusion Saccharomyces boulardii can be effective in the prevention of antibiotic associated diarrhea in children.%目的：研究并探讨布拉氏酵母菌在预防小儿抗生素相关性腹泻中的临床疗效。方法于2014年1月~2015年12月，选取240例给予抗生素治疗的小儿患者作为此次研究的对象，采用抛掷硬币法随机分成对照组、观察组，每组120例。两组患者均给予抗生素对症治疗，观察组在治疗期间加用布拉氏酵母菌。结果观察组的继发性腹泻发生率为9.17%，低于对照组的20.83%（P＜0.05）。与对照组相比，观察组腹泻患者的腹泻持续时间更短（P＜0.05）。结论布拉氏酵母菌可有效预防小儿抗生素相关性腹泻的发生。