25，27-二（α，γ-二酮苯丁氧基）-26，28-二羟基杯［4］芳烃的合成

摘要

以对叔丁基杯[4]芳烃为原料脱除叔丁基得到杯[4]芳烃，再经醚化、缩合两步反应首次合成25，27-二（α，γ-二酮苯丁氧基）-26，28-二羟基杯[4]芳烃，其结构经1 H NMR、13 C NMR、MS及元素分析表征。研究表明，目标化合物中的α，γ-二酮结构存在酮醇异构现象，在溶液中其酮醇异构体比例近似为1∶2。%25,27-Di(α,γ-diketophenylbutoxy)-26,28-dihydroxy calix[4]arene was synthesized by a two-step reaction of etherifica-tion and condensation from calix [4] arene,which was prepared by p-tert-butylcalyx [4] arene as the raw material via dealkyla-tion.The structure of title compound was characterized by 1 H NMR,13 C NMR,MS and elemental analysis.The results also indicated that keto-enol tautomerism of the α,γ-diketo motif of the title compound was observed and the ratio of the keto-enol isomer approxi-mately was 1:2.