以可再生生物质资源莽草酸为原料,在经酯化和2-碘酰基苯甲酸( IBX)氧化制得3-脱氢莽草酸甲酯的基础上,研究了在不同反应溶剂中和不同反应温度下,3-脱氢莽草酸甲酯分别与水合肼、乙酰肼、苯肼和乙酰胺选择性地得到非芳构化、部分芳构化和芳构化产物的反应.该方法具有选择性高、操作简单和条件温和等优点,为可再生非粮生物质资源莽草酸的利用提供了一种新的思路.%The purpose of this paper is to achieve the high value-added and diversified transformation of the renewable biomass (-) -shikimic acid, starting from which, the key intermediate ( -)-methyl-3-dehydro-shikimiate was readily obtained through esterification and 2-iodoxybenzoic acid-oxidation. The reaction of (-)-methyl-3-dehydroshikimiate with hydrazine, acethydrazide, hydrazinobenzene and acetamide could give rise to non-aromatization products (2a and 2d) , partial-aromatization products (2b) and aromatization products (2c and 2e) selectively under different conditions. The present methodology with good diversity, high selectivity and operational simplicity provides a new paradigm for the transformation of bio-based and non-food feedstock.
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