芽胞杆菌肽聚糖水解酶的功能研究进展

摘要

Over the years, peptidoglycan hydrolases are considered destructive roles, for example the phage lysis host use them to release the virus particles, some bacterias dissolve their competitors, etc. But in recent years, with the continuous research depth found:in cell growth and metabolism process, its positive roles are more important. This paper reviewed the functions of peptidoglycan hydrolase in Bacillus throughout the cell life course, including cell growth, division, motility, sporulation and spore germination, protein secretion, information transmission, innate immunity and other aspects, laid the theoretical foundation for the study of peptidoglycan hydrolases and cell metabolism in Bacillus and the other microorganism.%长久以来，肽聚糖水解酶都被认为是破坏性的角色，如噬菌体利用它裂解宿主以释放病毒粒子，一些细菌分泌它来溶解竞争对手等。但近几年来，随着研究的不断深入发现，在细胞生长代谢过程中，它的积极作用更为重要。综述了芽胞杆菌肽聚糖水解酶在细胞整个生命过程中的功能，包括细胞生长、分裂、能动性、芽胞形成及萌发、蛋白分泌、信息传递、先天性免疫以及致病性各个方面，为研究芽胞杆菌及其他微生物中肽聚糖水解酶和细胞代谢调节奠定了理论基础。