意识指数与脑电双频指数监测靶控丙泊酚全麻诱导时镇静深度的比较

摘要

目的 探讨意识指数(IOC)与脑电双频指数(BIS)相比,靶控丙泊酚全麻诱导时用于监测镇静深度的相关性.方法 纳入行基本外科或妇产科手术的患者30例,靶控丙泊酚全麻诱导期间,同时监测IOC和BIS.记录镇静评分(OAA/S)由5分逐级降低至1分时,每次OAA/S评分即刻的IOC及BIS值,以及相应点的丙泊酚效应室浓度.结果 与基线值比较,OAA/S评分从5逐渐降低至1时,BIS与IOC值均降低,BIS值之间或IOC值之间的差异均有统计学意义(P＜0.05).结论 IOC用于靶控丙泊酚全麻诱导时的镇静深度监测,与BIS具有良好的相关性.%Objective To compare a new level of consciousness monitor, called the index of consciousness (IOC) with the bispectral index (BIS) during propofol target-controlled infusion (TCI) anaesthesia induction. Methods After ethical committee approval and written patient consent, data from 30 patients were recorded. All patients were induced with propofol target-controlled infusion ( TCI) , until the Observer's Assessment of Alertness and Sedation (OAAS) scale level 1 was reached, and then IOC and BIS were calculated during OAAS 5 - 1. Results With the increase of sedation during OAAS 5 ～ 1, there was a significant decrease of BIS and IOC ( P < 0. 05 ). Conclusions IOC has a close correlation with BIS during propofol target-controlled infusion (TCI) anaesthesia induction.