目的 探讨显微血管减压手术对偏侧面肌痉挛(HFS)患者生活质量的影响.方法 收集2012年至2017年于北京协和医院神经外科行微血管减压手术治疗的224例偏侧面肌痉挛患者的临床资料.分别于手术前及手术后6个月进行痉挛强度(Cohen量表)和特异性生活质量( HFS-8量表)相关测评,并对结果进行统计分析.结果 手术后6个月时患者Cohen分级较治疗前明显下降,手术后6个月明显缓解率为92.7%,总有效率为97.6%;治疗后本HFS-8量表评分为2.71±3.25,显著低于术前的18.01±4.57(P＜0.05);以术前痉挛强度分组,不同痉挛强度的患者HFS-8量表评分明显改善(P＜0.05);HFS-8评分与痉挛强度显著相关( P＜0.001).结论 微血管减压术治疗面肌痉挛的疗效确切,并可有效改善HFS患者的生活质量.%Objective To investigate the impact of microvascular decompression surgery on quality of life in patients with hemifacial spasm. Methods A clinical data collection of 224 adult patients with hemifacial spasm treated by the surgery was conducted from 2012 to 2017. The degree of spasm and effect of the operation was evaluated by Co-hen grading standard before and after the surgery. The quality of life was evaluated by the HFS-8 scale. The results were statistically analyzed. Results According to Cohen grading standard, symptoms were improved significantly 6 months after the surgery. The effective remission rate and the total effective rate of the surgery were 92.7% and 97.6% respectively. The score of HFS-8 scale was significantly lower than before treatment (2.71±3.25 vs 18.01± 4.57, P＜0.05) ; The scores were significantly different before and after the surgery in patients with different de-grees of remission, except for the " invalid" group ( P=0.071) ; The scores of patients with different strengths of the spasm were significantly improved ( P＜0.05) , and the Pearson correlation coefficient suggested that the HFS-8 score was significantly correlated with the severity of the spasm. Conclusions Microvascular decompression is one of the preferred treatment of hemifacial spasm, which can effectively improve the the quality of life in patients with hemifacial spasm.
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