Objective To analyze the mood status and its influencing factors in the patients with Graves' disease. Methods In the study,213 patients with Graves' disease were recruited. The questionnaires including self-rating depression scale (SDS),self-rating anxiety scale ( SAS) and general information questionnaire were used to collect the data of sociology and demographic information,de-pression as well as anxiety of the patients. Univariate analysis was used to analyze the mood status and its influencing factors. ResultsAmong the patients with Graves' disease,the incidence of depression was 45. 0%,and the incidence of anxiety was 42. 6%. The influ-encing factors of depression status in the patients with diffuse goiter were gender,educational background and history of depression,and the influencing factors of anxiety status in the patients with diffuse goiter were gender,educational background,household income and anxiety history. The levels of blood triiodothyronine and thyroxine in the Graves' disease patients with anxiety or depression were lower than those patients without anxiety or depression. Conclusions Hyperthyroidism may increase the risk of developing mood disorders, and the occurrence of mood disorders in the patients with Graves' disease is correlated with their individual characteristics.%目的：研究弥漫性甲状腺肿伴甲亢患者的情绪现状及其影响因素。方法以该院213例弥漫性甲状腺肿伴甲亢患者为研究对象，采用自评问卷(包括抑郁自评量表、焦虑自评量表、一般资料问卷等)的方式收集患者的人口社会学资料以及抑郁、焦虑、工作压力源等资料，再采用单因素分析的方法研究患者的情绪现状及其影响因素。结果在弥漫性甲状腺肿伴甲亢患者中抑郁的发病率为45.0%；焦虑的发病率为42.6%。影响弥漫性甲状腺肿伴甲亢患者抑郁情况的因素有性别、文化程度和抑郁史，而影响弥漫性甲状腺肿伴甲亢患者焦虑情况的因素有性别、文化程度、家庭年收入和焦虑史。弥漫性甲状腺肿伴甲亢病人中抑郁或焦虑者的血三碘甲状腺原氨酸水平和血甲状腺素水平都较非抑郁或非焦虑者低。结论弥漫性甲状腺肿伴甲亢增加了抑郁和焦虑的发病率。弥漫性甲状腺肿伴甲亢患者并发情绪障碍的风险与其个体特征有关。
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