PDCA法规范某院注射用还原型谷胱甘肽用法的效果分析

摘要

Objective To explore the effect of PDCA method on the use of reduced glutathione for injection in a Hospital.Methods We analyzed the clinical application of reduced glutathione for injection in our hospital before and after the intervention of PDCA,summarized the irrational drug use performance and its possible reasons,and analyzed the effect of rational drug use.Results After PDCA method intervention,the reasonable rate of reduced glutathione for injection in our hospital increased from 19.4% to 37.1%.Among them,the phenomenon of dose deviation from 59.7% to 46.4%;no indication to the drug from 11.9% down to 3.1%;the proportion of the off-label drug use which were not registered down from 11.9% to 2.1%.Conclusions The clinical application effect of PDCA method on the reduced glutathione for injection in our hospital was significant,which is worth recommending.%目的 探讨PDCA法规范某院注射用还原型谷胱甘肽用法的效果.方法 分析PDCA法干预前后,某院注射用还原型谷胱甘肽的临床使用情况,总结其不合理用药表现及其可能原因,分析干预后合理用药改进效果.结果 PDCA法干预后,某院注射用还原型谷胱甘肽用药合理率由干预前19.4%上升为37.1%.其中,剂量偏大现象由59.7%降为46.4%;无适应证给药由11.9%降为3.1%;超说明书用药未备案比例从11.9%降至2.1%.结论 PDCA法规范某院注射用还原型谷胱甘肽的临床应用效果显著,值得推荐.