2014年老年病房内铜绿假单胞菌感染状况及其耐药性分析

摘要

Objective To investigate theinfection situation and drug resistance of Pseudomonas aeruginosa in Department of Geriatricsin a hospital.Methods Sputum,urine,and blood samples were collected during the year of 2014.The bacteria identification and drug sensitivity analysis were done by using VITEK 2 compact.Results There were 29 Pseudomonas aeruginosa cases from sputum and urine samples detected in 63 bacteria cases with the detecting rate of 46.03％;26 (89.66％) cases were from sputum samples whereas 3 (10.34％) cases were from urine.Among all detected Pseudomonas aeruginosa cases,16(55.17％) of them were multi-resistant.Drugs with resistance rate less than 10％ were Amikacin,gentamicin and tobramycin;drugs with resistance rate higher than 80％ were piperacillin,cefazolin,ceftriaxone,cefotetan,cotrimoxazole,and nitrofurantoin,and the resistance rate of imipenem was 13.79％.Conclusion Elderly patients are susceptible to Pseudomonas aeruginosa infection with clinical manifestation of pneumonia anda high rate of antibiotics resistance.%目的 分析老年病房内铜绿假单胞菌的感染状况及耐药情况.方法 收集2014年l～12月安徽省立医院老年内分泌科临床感染患者的痰、尿或血标本,采用法国梅里埃公司的VITEK2 Compact进行细菌鉴定及药敏实验.结果 共检出63株细菌,其中铜绿假单胞菌共29株,占46.03％.29株铜绿假单胞菌中,痰培养阳性26株(89.66％),尿培养阳性3株(10.34％).多重耐药的铜绿假单胞菌16株,占55.17％,耐药率低于10％的药物有阿米卡星、庆大霉素和妥布霉素,耐药率超过80％的有哌拉西林、头孢唑林、头孢曲松、头孢替坦、复方新诺明和呋喃妥因,对亚胺培南的耐药率为13.79％.结论 老年患者是铜绿假单胞菌的易感人群,临床多表现为肺部感染,细菌耐药率高.