In this paper,we mainly introduced the working principle,choice of matrix,the application and the limitations of MALDI-TOF MS in analysis of polymers. In addition,we prospected the develop-ment prospects of MALDI-TOF MS in the future.%近年来,基质辅助激光解吸电离飞行时间质谱(MALDI-TOF-MS)作为一种新型的软电离质谱技术,具有有快速、准确、灵敏度高、检测范围广等特点,在化学、生物,医疗卫生等众多领域得到广泛研究和应用。本文着重介绍了 MALDI-TOF-MS 的工作原理,基质的选择,该技术在聚合物分析中的应用进展,以及存在的问题,并对其发展前景作出展望。
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