急性心肌梗死和心源性猝死是大多数患者冠状动脉疾病的首发表现, 识别发生急性冠脉综合征的高风险患者是当代心血管成像的主要挑战.早期识别和准确评价易损斑块, 可有效地预防和降低不良事件的发生.由计算机断层扫描血管造影开发的易损斑块特点包括:斑块体积大、低衰减斑块、正性重构、点状钙化及餐巾环征.现介绍易损斑块详细形态特点及其临床价值, 同时描述非侵入性检查成像技术——计算机断层扫描血管造影对易损斑块检测的最新进展及优缺点.%Acute myocardial infarction and sudden cardiac death are the first manifestations of coronary artery disease in most patients. Identifying the high-risk patients with acute coronary syndrome is a major challenge for contemporary cardiovascular imaging. Early identification and accurate evaluation of vulnerable plaque can effectively prevent and reduce the occurrence of adverse events. Vulnerable plaque features developed by computed tomography angiography include large plaque, low-attenuation plaque, positive remodeling, spotty calcification, and napkin-ring sign. This article describes the detailed features and clinical value of vulnerable plaques, and describes the latest developments, advantages and disadvantages of non-invasive imaging techniques for computed tomography angiography for vulnerable plaque detection.
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