我们以往的研究表明,模拟电针可以引起循经电信息的传递,P物质和谷氨酸等兴奋性递质参与此过程.我们近期的研究表明,除了兴奋性递质外,内源性的抑制性递质生长抑素也可通过其外周受体抑制穴位支配神经电活动,并且对电针引起的循经电信息传递发挥抑制作用.穴位局部生长抑素与谷氨酸之间存在相互作用.上述研究表明,兴奋性递质和抑制性递质之间的动态平衡对于维持经络活动起着重要作用.%Our previous studies have showed that analogue electroacupuncture (EA) could induce a transmission of electrical signals along meridians, and excitatory neurotransmitters such as substance P and glutamate were involved in the transmission process. In recent studies, our results showed that somatostatin and its receptors played a dose-dependent tonic inhibition on the discharge rates of original and adjacent nerves innervating the acupoints. In addition, there existed an interaction between somatostatin and glutamate. These results suggest that the balance between excitatory and inhibitory neurotransmitters plays an important role in the function activities of acupoints and meridians.
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