Sleep deprivation(SD),a very common phenomenon in modern society,has been become one of the most significant medical problems because of its detrimental effects on human’s health. This paper reviewed the SD related studies in recent years and gave a brief summary on the research methods of SD and the effects of SD on learning and memory,with a particular focus on the changes of genes and proteins affected by SD in central nervous system.%当代社会的各种主客观因素,使得睡眠剥夺的发生成为常态,其对人们生活的不良影响正日益突显,为国内外研究热点。该文回顾了近年来睡眠剥夺研究的相关文献,概述了研究方法及其对学习记忆的影响,着重分析了睡眠剥夺对中枢神经系统相关基因和蛋白变化的影响。
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