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2型糖尿病影响因素的病例对照研究

         

摘要

目的:分析2型糖尿病患者患病的相关危险因素,进一步探讨相应的预防控制措施.方法:采用病例对照研究的流行病学方法,选取124例2型糖尿病住院患者及125例在体检中心进行体检的无糖尿病者作为对照,用自行设计的调查问卷对两组人群进行问卷调查,同时进行体格检测.结果:有糖尿病家族史(OR=4.448)、主食以米为主(OR=21.165)、吸烟(OR=2.821)、睡眠质量差(OR=3.040)、有熬夜习惯(OR=7.235)、性格内向(OR=11.424)、SBP(OR=1.048)、焦虑(OR=4.106)、TC(OR=26.654)、DBiL(OR=2.208)是2型糖尿病发生的危险因素(OR>1,P<0.05);而饮茶(OR =0.159)、蔬菜摄入量(OR =0.964)则起保护作用(OR<1,P<O.05).结论:2型糖尿病是多因素共同作用的结果,应采取综合措施加强2型糖尿病的防范工作.%Objective:To explore the risk factors associated with type 2 diabetes mellitus(T2DM) for providing scientific evidences for the disease control and prevention. Methods: By case-control study, we conducted epidemiological investigation in 124 type 2 diabetics on hospital basis and recruited 125 subjects confirmed healthy in the medical examination center controls,and carried out the survey on the two groups using self-programmed questionnaire and medical check-up on the total subjects. Results; Multivariate unconditional logistic regression analysis suggested that susceptible risk factors of T2DM were associated with family history of diabetes mellitus (OR = 4. 448) , rice for staple foods ( OR = 21. 165), smoking (OR = 2.821) ,poor sleep quality (OR =3.040),habits of staying up late ( OR = 7.235 ) , introverted personality (OR = 11.424), SBP (Oft = 1.048), anxiety ( OR =4. 106) ,TC (0R = 26.654) and DBiL (OR =2.208) (OR > l',P <0.05),whereas tea drinking (OR =0.159) and quantity of daily vegetable intake (OR = 0.964) were positive effects (OR < 1 ,P< 0. 05 ). Conclusion-. Prevention of T2DM should be involved in comprehensive measures since this disease can be the results of multiple causative factors.

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