代谢组学在心血管疾病方面的研究进展

摘要

Metabonomies is a systematic science that mainly studies the dynamic changes of endogenous metabolites after a biological system is stimulated or disturbed. Its application in cardiovascular diseases has increasingly been explored, with an attempt to find valuable biomarkers and explore the underlying patho-genesis of cardiovascular diseases by profiling the metabolism in these patients. This article summarized recent advances in this topic and outlines prospects for future developments.%代谢组学是研究生物体被扰动后内源性代谢物变化规律的系统科学,其在心血管疾病中的应用研究成为热点,有望通过对心血管病患者的代谢轮廓分析寻找到有意义的生物标记物并探索疾病的发病机制.本文就研究现状做一综述,并对其发展前景进行展望.