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Manipulation of nanoparticles and biological samples through enhanced optical forces.

机译:通过增强的光学力来操纵纳米颗粒和生物样品。

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摘要

Non-invasive optical manipulation of particles has emerged as a powerful and versatile tool for biological study and nanotechnology. We propose and demonstrate large scale nanoparticle assembly using opto-thermal force produced by conventional optical tweezers. This method is shown to allow precise concentration and assembly of particles including carbon-nanotubes, VO2 nanorods, and CdTe quantum dots. Assembled devices were shown to have good contact with patterned electrodes. In addition, we propose and demonstrate a purely optical approach to rotate and align particles using the interaction of polarized light with photonic crystal nanostructures to generate enhanced trapping force. With a weakly focused laser beam we observed efficient trapping and transportation of polystyrene beads with sizes ranging from 10 microm down to 190 nm as well as cancer cell nuclei. In addition, we demonstrated alignment of non-spherical particles using a 1-D photonic crystal structure. Bacterial cells were trapped, rotated and aligned with optical intensity as low as 17 microW/microm 2. This approach can be extended to using 2-D photonic crystal nanostructures for full rotation control.
机译:粒子的无创光学操纵已成为生物学研究和纳米技术的强大而多功能的工具。我们提出并展示了使用常规光学镊子产生的光热力进行的大规模纳米粒子组装。该方法显示出可以精确地浓缩和组装包括碳纳米管,VO2纳米棒和CdTe量子点在内的颗粒。显示组装的装置与图案化的电极具有良好的接触。此外,我们提出并演示了一种纯粹的光学方法,利用偏振光与光子晶体纳米结构的相互作用来旋转和对齐粒子,以产生增强的俘获力。使用弱聚焦的激光束,我们观察到有效捕获和运输尺寸从10微米到190 nm的聚苯乙烯珠以及癌细胞核。此外,我们演示了使用1-D光子晶体结构排列非球形粒子的过程。细菌细胞被捕获,旋转并以低至17 microW / microm 2的光强度排列。该方法可以扩展到使用2-D光子晶体纳米结构进行完全旋转控制。

著录项

  • 作者

    Wilson, Benjamin.;

  • 作者单位

    University of Washington.;

  • 授予单位 University of Washington.;
  • 学科 Engineering Electronics and Electrical.;Physics Optics.
  • 学位 Ph.D.
  • 年度 2009
  • 页码 95 p.
  • 总页数 95
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

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