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Etude biomecanique de l'effet immediat et a long terme de chirurgies costales pour le traitement des scolioses

机译:肋骨外科治疗脊柱侧弯近期和长期效果的生物力学研究

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摘要

Idiopathic scoliosis is a complex three-dimensional (3D) deformity of the spine and the rib cage. In the case of a severe spinal curve, patients are generally treated by surgical instrumentation and fusion of the deformed spine segment. In front of significant rib cage deformity (rib hump), thoracoplasty, a cosmetic surgery that consists to resect rib segments, is an option. It is generally accepted that scoliosis progresses by a self-sustained biomechanical cycle due to unbalanced loading of the spine, which alters bone growth. Hence, some authors proposed that rib surgeries (resection, shortening or lengthening) could reestablish the force balance transmitted to the spine, and consequently reverse or slow down scoliotic deformation progression. These innovative surgical concepts were tested in experimental studies on animals and in a few clinical studies. However, these rib surgeries remain empirical procedures for which a large number of variables needs to be controlled. A biomechanical study was achieved in order to clarify the action mechanisms of the rib surgeries and to explore the influence of the surgery parameters.;The present project is a continuation of this study. It encloses two main parts with the first one concerned by the immediate effect of rib surgeries. This part aims at developing a method to examine more thoroughly the influence of the surgery parameters and to identify the parameters maximizing the correction of the scoliotic deformities. The second part of the project aims at developing a biomechanical modeling that will enable to simulate the long-term effect of rib surgeries. Consequently, bone growth and growth modulation by load resulting from the surgery must be represented in the model. (Abstract shortened by UMI.).
机译:特发性脊柱侧弯是脊柱和肋骨笼的复杂三维(3D)畸形。在严重脊柱弯曲的情况下,通常通过手术器械和融合的脊柱节段治疗患者。在出现严重的肋骨畸形(肋骨隆起)之前,可以选择胸廓成形术,即切除肋骨段的整容手术。人们普遍认为,由于脊柱负荷不平衡,脊柱侧弯通过自我维持的生物力学周期发展,从而改变了骨骼的生长。因此,一些作者提出肋骨手术(切除,缩短或延长)可以重新建立传递到脊柱的力平衡,从而扭转或减慢脊柱侧弯变形的进程。这些创新的外科手术概念已在动物实验研究和一些临床研究中得到测试。但是,这些肋骨手术仍然是经验性程序,需要控制许多变量。为了阐明肋骨手术的作用机理并探讨手术参数的影响,进行了一项生物力学研究。本项目是这项研究的延续。它包括两个主要部分,第一个涉及肋骨手术的即时效果。本部分旨在开发一种方法,以更彻底地检查手术参数的影响并确定使脊柱侧凸畸形矫正最大化的参数。该项目的第二部分旨在开发生物力学模型,该模型将能够模拟肋骨手术的长期效果。因此,必须在模型中表示骨骼生长和由手术引起的负荷引起的生长调节。 (摘要由UMI缩短。)。

著录项

  • 作者

    Carrier, Josee.;

  • 作者单位

    Ecole Polytechnique, Montreal (Canada).;

  • 授予单位 Ecole Polytechnique, Montreal (Canada).;
  • 学科 Biomedical engineering.
  • 学位 M.Sc.A.
  • 年度 2004
  • 页码 188 p.
  • 总页数 188
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

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