Effect of inhibition on apoptosis of bEnd.3 cells induced by terahertz radiation

摘要

The use of terahertz radiation in various fields such as biology and medicine is increasing every year. Meanwhile, people are increasingly concerned about the mechanism on the interaction between terahertz radiation and biological system. In this study, we evaluated the effect of the cellular response of bEnd.3 which exposing to the terahertz radiation in the range of 0.1-3.5 THz. We collected the spectral data of cells during the irradiation with a temperature of 20.6°Cand a relative humidity of 5%. Meanwhile, the apoptosis of cell was assessed by Annexin V-FITC/PI kit. As a result, the apoptosis of cells were inhibited from 0 and 6 hours after terahertz irradiation and promoted at 12 hours after irradiation. Moreover, we also calculated the complex dielectric constant of bEnd.3 cells at different exposures. The results demonstrate that the dielectric loss of cells showed a slight decrease with the increase of exposure in the range of 0.2-1.4 THz.