A Novel Alignment-Free Method for Phylogenetic Analysis of Protein Sequences

摘要

Up to now, various approaches for phylogenetic analysis have been developed. Almost all of them put stress on analyzing nucleic acid sequences or protein primary structures. In this paper, we take the physicochemical properties of amino acids into account and introduce the protein feature sequences into phylogenetic analysis by using the Bhattacharyya distance. We find that this method is effectual and feasible.