Development of poly-3-hexylthiophene based ISFET sensors for biomedical applications

摘要

Ion-sensitive Field-Effect Transistors (ISFETs) have been applied for in vitro and online detection for clinical purposes such as concentration of urea, penicillin-G and potassium ion (K+). They have proven to be highly sensitive, shown less response time, reproducible and smaller than the piecewise assembled conventional biosensors. Materials like p3HT, Tantalum Oxide and PVA-SbQ have show their merit as components of various FETs fabricated on silicon substrate. This paper discusses the feasibility of using them together along with design enhancements such as zigzag inter-digitated electrode. The results hitherto obtained have been analyzed and conclusions are drawn to set future course of experimentation to develop the ISFET for sensor applications.