Studies on Synthesis and Evaluation of Peptide–Polyamine Conjugate from Marine Origin

摘要

Aculeines (ACUs) are modified peptide toxins isolated from the marine sponge Axinyssa aculeata. ACU-A and -B are comprised of a common 44- amino acid ribosomal peptide (AcuPep) conjugated with modified tryptophan residues named protoaculeines (pACUs).