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A multichannel analog front-end for recording neural electrical signals

机译:用于记录神经电信号的多通道模拟前端

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Recent work in the field of neurophysiology has demonstrated that it is possible to reveal the nature of “memory” and “thinking” which helps to understand how brain works, by means of observing the firing characteristic of action potentials (AP) and the exchange pattern of signals between neurons. To address these needs, we have developed a prototype of a fully integrated circuit for neural recording on a Micro-Electrode Array (MEA). In this scheme, the MEA is composed by 64 electrodes and 2 reference electrodes. The proposed integrated circuit has an area of 5×5 mm2, including 8 recording channels. Each channel can operate independently to execute amplifying, filtering, etc. The circuits are designed and simulated in a standard 0.5µm CMOS technology. According to the simulation results, this chip is able to record AP signal from neurons.
机译:最近在神经生理学领域的工作表明,通过观察动作电位(AP)和交换模式的射击特性,有助于了解大脑如何工作的“记忆”和“思维”的性质。神经元之间的信号。为满足这些需求,我们开发了一种全集成电路的原型,用于微电极阵列(MEA)上的神经记录。在该方案中,MEA由64个电极和2个参考电极组成。所提出的集成电路的面积为5×5mm 2 ,包括8个记录通道。每个通道可以独立地操作以执行放大,过滤等。电路是在标准的0.5μmCMOS技术中设计和模拟的。根据仿真结果,该芯片能够从神经元记录AP信号。

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