Bovine Viral Diarrhea Virus Infections in Heterologous Species: Implications for Diagnosis and Control

摘要

Bovine viral diarrhea virus (BVDV) is an economically important pathogen of cattle worldwide, producing a wide range of clinical manifestations including reproductive losses and gastrointestinal or respiratory disease. BVDV is the prototypic member ofthe genus Pestivirus within the family Flaviviridae. The International Committee on Taxonomy of Viruses (ICTV) currently recognized four species within this genus: BVDV-1, BVDV-2, classical swine fever virus (CSFV), and border disease virus (BDV). Additionally, a growing number of related, but as yet unclassified, pestiviruses from various domestic and wild animal species hasbeen described including pronghorn virus, Bungowannah virus, giraffe pestivirus, 'HoBi'-like pestiviruses, Aydin-like pestiviruses, rat pestivirus, bat pestivirus, atypical porcine pestivirus, Tunisian sheep pestiviruses, and Linda virus.