Perioclontitis - risk factors of atherosclerosis?

摘要

The effect of active periodontal treatment on progression of the disease and the role of in vitro immune reaction after activation of peripheral blood mononuclear cells were studied. The genotype was analyzed and serological predisposition to disease was studied. The first group of 20 patients at the begining of the study was conservatively treated for 15 years. The second group consisted of 10 patients diagnosed as moderate periodontitis. The control group was formed from healthy persons of similar age. Slow progression of the disease was found in 10 patients and after 10 years the progressive form of the disease was found in another 10 patients. The risk composite genotype IL-1 and risk alleles of Apo-E were present more frequently in patients with progressive periodontitis. 23,3 % of patients had increased serum atherosclerosis index.