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Induction of Apoptosis and G2/M Cell Cycle Arrest by Myricetin in Human Hepatoma HepG2 Cells

机译:人肝瘤Hepg2细胞中Myricetin诱导细胞凋亡和G2 / M细胞周期捕获

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The article is about induction of apoptosis in human hepatoma HepG2 cells by myricetin (MYR). The human hepatoma HepG2 cells was treated with different doses myricetin for 72h. Cytotoxicity was evaluated by SRB assay, apoptosis-related alterations in morphology ascertained by cytochemical staining (Hoechst 33258) and transmission electron microscopy (TEM). The cell cycle and apoptotic rate were quantified by flow cytometry (FCM).
机译:本文是关于Myricetin(MYR)的人肝癌HepG2细胞中凋亡的诱导。将人肝癌HEPG2细胞用不同的剂量myricetin处理72h。通过SRB测定评估细胞毒性,通过细胞化学染色(Hoechst 33258)和透射电子显微镜(TEM)确定的形态学的细胞凋亡相关的改变。通过流式细胞术(FCM)量化细胞周期和凋亡率。

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