Gold Nano-Probes as Targeted CT Contrast Agents for In-vivo cancer Imaging

摘要

This paper describes a new class of immuno-tareeted and cancer specific CT contrast agents, which enable CT imaging of cancer at cellular and molecular resolution. The method is based on the development of gold nano-probes that specifically and sensitively target in vivo tumor specific antigens, while inducing distinct contrast in CT imaging (increased x-ray attenuation). The overall goal of this research is to develop a novel cancer imaging tool, which may lead to improvements in therapy due to early detection, accurate staging and micro-tumor identification.