Robustness and Learning of Circadian Clocks against Changes of Environments based on Error Feedbacks

摘要

In this paper, it is considered why and how circadian rhythms have about 24 hours in view of evolution. This research is theoretical in systems biology based on the systems and control theory. One of evolution architectures is proposed for circadian rhythms using adaptive learning systems with error feedbacks. Error feedbacks update some parameters in systems which describe circadian rhythms according to environments such as the sun rise and the sun set. First our proposed evolution architectures show no circadian rhythms because adaptive learning systems have no data. But as time goes on, the output of our proposed evolution architectures show circadian rhythms and finally converge rhythms with the about 24 hours period.