A Study of Inclusion Complex of Miconazole Nitrate with p-cyclodextrin and its Application on Fabrics

摘要

Inclusion complex of miconazole nitrate with P-cyclodextrin (P-CD) was prepared by the coprecipitation method The constants and ratio of inclusion complex (1:1) were determined by phase solubility method. The DSC curve verified the inclusion complex formation between P-CD and miconazole nitrate. The anti-bacterial textiles can be obtained by treating fabrics with the prepared inclusion complexes, The results show the durability of the treated fabrics is pretty good, which keeps the ability of anti-bacteria above 70% after washing 10 times.