Apatite formation in body environment is known to be essential for materials to show bone-bonding ability, i.e. bioactivity. The present authors have recently revealed that organic-inorganic hybrids synthesized from vinylsulfonic acid sodium salt (VSAS) and calcium chloride (CaCl_2) by modification with 2-hydroxyethylmethacrylate (HEMA) form apatite on their surfaces in simulated body fluid (SBF). In the present study, effect of calcium salt on bioactivity of the hybrids was examined in SBF. The crack-free hybrids exhibiting apatite-forming ability were successfully obtained, when content of calcium chloride was fixed at 5 mol percent to the total of VSAS and HEMA.
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