We discuss measurements of anisotropy in the Cosmic Microwave Background (CMB) from the first season of observations with the Degree Angular Scale Interferometer (DASI). The instrument was deployed at the South Pole in the austral summer 1999-2000, and made observations throughout the following austral winter. We have measured the angular power spectrum of the CMB in the range 100 < l < 900 in nine bands, with fractional uncertainties in the range 10-20%, dominated by sample variance. By comparison of the DASI+COBE-DMR data with a seven-dimensional grid of adiabatic CDM models, we find Ω{sub}bh{sup}2 = 0.022{sub}(-0.003){sup}(+0.004), consistent with that derived from measurements of the primordial abundance ratios of the light elements combined with big bang nucleosynthesis theory. Limits on other cosmological parameters are presented.
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