STRATEGIES FOR EXTRACTION METHODS IN THE EXTRACTIVE FERMENTATION PROCESS OF CARBOXYLIC ACID

摘要

Extractive fermentation affords a means of avoiding product inhibition by the removal of product during the fermentation process. The fermentation broth of the carboxylic acid is a solution with low concentration, multiple components and high pH. The lower content of solvent can be used, that is also good for reducing the toxic to bacteria. Higher concentration ratio of product to the other component is benefit for obtaining higher purity of the product. The extractive fermentation can be carried out by attaching the extractor to the homolactic fermentor, even the homoacetic fermentation process run at higher pH. 94% purity of acetic acid can be obtained by controlling the concentration ratio in the extractive fermentation. The concentration ratio at inlet of extractor is constant for parallel fermentation process. The higher purity of the product still can be obtained by using the fractional extractor.