Optimisation of porous silicon carrier matrices applied in chip based micro enzyme reactors

摘要

Porous silicon is generated in five different silicon types of (111)-orientation and the influence of dopant type and dopant concentration with respect to ability to serve as an enzyme activated biocatalytic substrate. Glucose oxidase was immobilised onto the porous surface and a maximum increase in catalytic efficiency of 350 times was demosntrated. The influence of the depth of the porous layer was investigated, showing that an average porous depth of no more than 5-10 mum is optimal for the parallel channel structured micro enzyme reactors developed by our group.