Radiosensitization by porphyrins in 60Co-irradiated cells of different natures

摘要

Efficiency of cell radiosensitization by porphyrins is a function of the irradiation dose, the nature of the cell and physico-chemical properties of the sensitizer. The maximal radio-sensitization for E. ascites tumor cells was reached at 2 Gy, for Saccharomyces cerevisiae-25Gy. The radiosensitization by different porphyrins in E.ascites tumor cells increases their cytotoxicity by a factor of 3, in Saccharomyces cerevisae - inhibition of growth 0.5 - 2.5 time.