Bringing the parts together: Steps towards an in-silico protocell

摘要

This article focuses on a system theoretic approach to synthetic biology, and in particular on the construction of a protocell model. The questions addressed here are: Which parts of functional modules are required to describe a protocell and which design methods are needed for self-replicating systems. We describe a model for an in-silico protocell that combines experimentally validated biological subsystems with theoretical studies.