Fabrication of an ISFET Sensor for the Detection of Sodium Ions in Body Plasma

摘要

Sodium chloride, commonly known as table salt, is widely used as essential seasoning in food, snacks and deserts worldwide. However, excessive consumption of table salt is a major cause of various health issues, involving high blood pressure, liver cirrhosis, kidney disease, and heart failure. This research aims at creating a portable, low-powered, efficient sensor for detection of sodium ions in body plasma for medical diagnosis purpose. The device was fabricated on a platform of Ion-Sensitive Field-Effect Transistor (ISFET) modified with sodium ionophore (sodium recognizing element), entrapped in polyurethane thin film. Our preliminary studies show that sodium ionophore-modified ISFET sensor yields good sensing performances, having a maximum sensitivity of 43 mV/pNa, and a detection limit of 2.3 millimol/liter.