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Adaptive threshold method based on PET measured lesion-to-background ratio for the estimation of Metabolic Target Volume from 18F-FDG PET images

机译:基于PET的自适应阈值方法测量了来自 18 F-FDG PET图像的代谢目标体积的损伤对背景比

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Most advanced radiotherapy planning can be optimized by incorporating the metabolic image of the tumour to be irradiated (Metabolic Target Volume). MTV can be properly obtained by in vivo molecular imaging studies as the volume of metabolically active tumour component. Positron EmissionTomography (PET) can provide MTV by in vivo measuring the glucose metabolism of a tumour. Aim of this work was to develop an innovative PET image segmentation method, based on an adaptive threshold of the image signal-to-noise ratio, for the estimation of the MTV. The proposed method was tested on a set of anthropomorphic phantoms proving its feasibility, operator-independency and accuracy in a clinical setting.
机译:可以通过结合肿瘤的代谢图像来优化最先进的放射疗法规划(代谢靶体积)。可以通过体内分子成像研究作为代谢活性肿瘤成分的体积正确获得MTV。正电子曝光斑块图像(PET)可以通过体内测量肿瘤的葡萄糖代谢提供MTV。这项工作的目的是通过基于图像信噪比的自适应阈值来开发一种创新的PET图像分段方法,用于估计MTV。在一组拟人体幽灵上测试了所提出的方法,证明其可行性,操作员 - 独立性和准确性在临床环境中。

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