STRUCTURAL MODIFICATION OF STREPTOCOCCUS CAPSULAR POLYSACCHARIDES BY MUTAGENESIS

摘要

The capsular polysaccharide (CPS) represents a key virulence factor for most encapsulated streptococci. Streptococcus suis and Group B Streptococcus (GBS) are both well-encapsulated pathogens of clinical importance in veterinary and/or human medicine and responsible for invasive systemic diseases. CPS differences are the basis for serological differentiation of the species into serotypes.